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Which Organic Acid is Produced by Glycolysis?

Published in Glycolysis Product 2 mins read

The primary organic acid produced by glycolysis is pyruvate.

Understanding Glycolysis

Glycolysis is a fundamental metabolic pathway that occurs in the cytoplasm of cells. Its main purpose is to break down glucose, a six-carbon sugar, into smaller molecules to generate energy in the form of ATP and NADH.

According to the provided reference:

  • "Through the process of glycolysis, one molecule of glucose breaks down to form two molecules of pyruvate."

This clearly identifies pyruvate as the end product of glycolysis.

Pyruvate: The End Product

Pyruvate (specifically, the anion form of pyruvic acid) is a vital three-carbon organic acid. It is the key molecule produced at the end of glycolysis.

What Happens to Pyruvate After Glycolysis?

The fate of pyruvate depends on the presence of oxygen:

  • Aerobic Conditions (with oxygen): Pyruvate is transported into the mitochondria where it is converted to acetyl-CoA and enters the Krebs cycle (citric acid cycle) for further oxidation and energy production.
  • Anaerobic Conditions (without oxygen): Pyruvate is converted through fermentation.
    • In humans and other animals, pyruvate is converted to lactate (lactic acid).
    • In yeast and some bacteria, pyruvate is converted to ethanol and carbon dioxide.

While lactate and ethanol are produced after glycolysis through subsequent fermentation pathways, pyruvate is the direct organic acid product of glycolysis itself, as stated in the reference.

Key Takeaway

Based on the reference and the definition of glycolysis, pyruvate is the specific organic acid molecule generated at the conclusion of this metabolic pathway.

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