Based on information regarding the immune system's role in fighting infections, 70–80% of immune cells are located in the gut.
The Gut: A Major Immune Hub
The majority of your body's immune cells reside within the digestive system, specifically in the gut. This is not surprising, as the gut is a primary point of contact between the body and the external environment, constantly interacting with food particles, beneficial microbes, and potential pathogens.
According to the provided reference:
With 70–80% of immune cells being present in the gut, there is an intricate interplay between the intestinal microbiota, the intestinal epithelial layer, and the local mucosal immune system.
This high concentration of immune cells facilitates a complex and dynamic relationship vital for health. The gut immune system must:
- Defend against pathogens: Be ready to identify and neutralize harmful bacteria, viruses, and other invaders ingested with food or present in the environment.
- Maintain tolerance: Coexist peacefully with the vast population of beneficial gut microbes (microbiota) and tolerate harmless food components.
- Interact with the gut lining: Work closely with the intestinal epithelial layer, which acts as a physical barrier.
This intricate interplay ensures that the gut remains healthy, preventing infections while also allowing for nutrient absorption and supporting the beneficial microbial ecosystem. Therefore, when considering "70% of your immune system," it refers to the significant portion of immune cells strategically positioned in the gut.
