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What is the RBC count in leukemia?

Published in Hematology 2 mins read

The RBC (red blood cell) count in leukemia can be lower than normal, normal, or even higher than normal, depending on the type of leukemia, the stage of the disease, and the individual's response to treatment. There isn't a single, definitive RBC count for leukemia patients.

Leukemia is a cancer of the blood-forming tissues, hindering the body's ability to fight infection and impacting red blood cell production. Because leukemia affects the bone marrow, where blood cells are produced, the production of red blood cells, white blood cells, and platelets can be disrupted.

Here's a breakdown of how leukemia can affect RBC count:

  • Anemia (Low RBC Count): This is a common finding in leukemia. The cancerous cells in the bone marrow can crowd out the normal cells that produce red blood cells, leading to a decreased RBC count and anemia.
  • Normal RBC Count: In some cases, especially in early stages or certain types of leukemia, the RBC count might be within the normal range. However, other blood cell counts (like WBC) might be abnormal.
  • High RBC Count (Rare): Some rare types of leukemia, like polycythemia vera (a type of chronic myeloproliferative neoplasm), can cause an elevated RBC count. While not technically a leukemia in the strictest sense, it's a related blood cancer.

Normal RBC Count Ranges (for reference):

Red cells (per microliter of blood)
Men 4.7–6.1 million
Women 4.2–5.4 million

It's important to remember that these are just reference ranges, and the specific normal range can vary slightly between laboratories.

In summary, leukemia can cause the RBC count to be lower, normal, or rarely, higher than normal. A comprehensive blood test, including white blood cell count, platelet count, and a bone marrow biopsy, is crucial for accurate diagnosis and treatment planning.

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