askvity

Which Organ Produces Platelets?

Published in Hematopoiesis 2 mins read

The bone marrow produces platelets. Specifically, it's the red bone marrow that's responsible. This spongy tissue, found inside bones, generates blood stem cells which then differentiate into various blood cells, including platelets.

Understanding Platelet Production

Platelets, also known as thrombocytes, are tiny blood cells crucial for blood clotting. Their creation is a complex process:

  1. Megakaryocytes: Large cells in the bone marrow called megakaryocytes are the precursors to platelets.
  2. Fragmentation: Megakaryocytes fragment, releasing thousands of platelets into the bloodstream.
  3. Continuous Renewal: Because platelets have a short lifespan (around 10 days), the bone marrow continuously produces new ones to maintain a sufficient supply.
  4. Regulation: The production of megakaryocytes and subsequently platelets is regulated by thrombopoietin, a hormone produced by the liver and kidneys.

Several sources confirm this:

While research explores in vitro platelet production methods, the primary and natural source remains the bone marrow.

Related Articles