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What Causes Hemoglobin to Drop?

Published in Hemoglobin Deficiency 3 mins read

Low hemoglobin levels, often a symptom of anemia, result from various factors affecting the body's ability to produce or maintain sufficient red blood cells. Hemoglobin is the protein in red blood cells responsible for carrying oxygen throughout the body. When hemoglobin levels drop, the body's oxygen supply is compromised.

Common Causes of Low Hemoglobin:

Several factors can lead to decreased hemoglobin:

1. Nutritional Deficiencies:

  • Iron Deficiency: This is the most common cause. Without enough iron, the body can't produce enough hemoglobin. This can stem from a poor diet or increased iron needs (e.g., during pregnancy) [Reference: 11-May-2023 source]. Blood loss from heavy menstrual bleeding, ulcers, cancer, or certain pain relievers (especially aspirin) also contributes to iron deficiency. [Reference: 11-May-2023 source].
  • Vitamin Deficiencies: Deficiencies in vitamins like vitamin B12 and folate are crucial for red blood cell production, so a lack of these can also lower hemoglobin levels. [Reference: Mayo Clinic Anemia article]

2. Blood Loss:

  • Internal Bleeding: Bleeding within the digestive tract (from ulcers, cancers, or hemorrhoids) or other internal sources causes significant hemoglobin loss. [Reference: Mayo Clinic Low Hemoglobin Count article]
  • Heavy Menstrual Bleeding: Excessive menstrual flow can deplete iron stores and lower hemoglobin. [Reference: Mayo Clinic Anemia article; Verywellhealth article]
  • GI Surgery: Surgery involving the gastrointestinal tract can lead to blood loss. [Reference: Verywellhealth article]

3. Underlying Medical Conditions:

  • Chronic Diseases: Conditions like autoimmune diseases, liver disease, thyroid disease, and inflammatory bowel disease can interfere with red blood cell production, resulting in lower hemoglobin. [Reference: Medical News Today article]
  • Kidney Disease: Chronic kidney disease (CKD) often leads to anemia due to reduced erythropoietin production, a hormone essential for red blood cell formation. [Reference: NIDDK Anemia in CKD article]
  • Cancer: Cancer and its treatments (e.g., chemotherapy) can suppress bone marrow function, reducing red blood cell production. [Reference: American Cancer Society article].
  • Aplastic Anemia: This rare condition occurs when the bone marrow fails to produce enough new blood cells, including red blood cells. This directly leads to a hemoglobin drop. [Reference: Johns Hopkins Aplastic Anemia article]

4. Bone Marrow Issues:

  • Reduced Red Blood Cell Production: Various conditions can impair the bone marrow's ability to produce red blood cells, causing a subsequent drop in hemoglobin levels. In newborns, a natural decrease in red blood cell production occurs during the first few weeks of life, resulting in a slow drop in hemoglobin. [Reference: Merck Manual Anemia in Newborn article; Cleveland Clinic Low Hemoglobin article]

Understanding and Addressing Low Hemoglobin

It is crucial to consult a healthcare professional for diagnosis and treatment of low hemoglobin. Treatment strategies vary depending on the underlying cause and may include dietary changes, medication (e.g., iron supplements), or addressing the underlying medical condition.

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