A Civatte body is a specific histological finding, appearing as a rounded, homogenous, eosinophilic mass.
Here's a more detailed breakdown:
- Appearance: Under a microscope, using routine Hematoxylin and Eosin (H&E) staining, Civatte bodies (CBs) are seen as rounded, homogenous, eosinophilic masses.
- Location: They are typically found in the deeper layers of the epidermis or epithelium, and also frequently in the dermis or connective tissue.
- Nomenclature:
- In epithelium/epidermis, they're known as Civatte bodies.
- In connective tissue, they may be referred to as colloid bodies or hyaline bodies.
- Significance: Civatte bodies are often associated with certain skin conditions, like lichen planus.
In summary, Civatte bodies are distinctive microscopic features characterized by their appearance, location and association with particular disease processes.
