Yes, hCG (human chorionic gonadotropin) increases testosterone levels.
How hCG Increases Testosterone
hCG mimics the luteinizing hormone (LH) in men. LH stimulates Leydig cells within the testicles to produce testosterone. By mimicking LH, hCG prompts these cells to increase testosterone production. This is supported by numerous studies showing increased testosterone levels after hCG administration compared to a placebo.
Evidence from Studies:
- Increased Testosterone Levels: Multiple studies have demonstrated that hCG significantly increases serum testosterone levels. One study showed a mean serum testosterone level significantly increased after hCG treatment. See source: https://pmc.ncbi.nlm.nih.gov/articles/PMC3214853/
- Improved Intratesticular Testosterone: hCG administration effectively improves intratesticular testosterone, the testosterone produced within the testicles themselves. See source: https://pmc.ncbi.nlm.nih.gov/articles/PMC6844348/
- Maintaining Sperm Production: In combination with testosterone therapy, hCG helps maintain adequate sperm production and testicle volume. See sources: https://houstonmenshealth.com/posts/gatekeepersofmen-series/hcg-and-testosterone-levels/ and multiple other provided sources
Practical Applications:
- Treatment for Low Testosterone (Hypogonadism): hCG is sometimes used to treat hypogonadism, although more research is needed to fully establish its effectiveness. See source: https://www.medicalnewstoday.com/articles/hcg-for-low-testosterone
- Male Infertility: hCG can increase testosterone and improve sperm production, making it a potential treatment for male infertility. See source: https://www.maleinfertilityguide.com/hcg
- Use with Testosterone Replacement Therapy (TRT): Combining hCG with TRT can help preserve testicular function and intra-testicular testosterone production. See source: https://themenshealthclinic.co.uk/the-benefits-of-using-hcg-with-trt/
Important Note: hCG is a hormone and should only be used under the supervision of a healthcare professional. Self-administering hCG can be dangerous.