Fluctuations in several hormones can contribute to a low mood, but estrogen and progesterone are particularly significant, especially in individuals with uteruses.
Here's a breakdown:
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Estrogen and Progesterone: These hormones significantly impact mood. Declining levels, particularly during menstruation, postpartum, or menopause, can lead to lower serotonin levels, increased irritability, anxiety, and sadness. The mood swings associated with hormonal fluctuations can decrease one's capacity to manage typical daily stressors.
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Serotonin: While not a hormone itself, serotonin is a neurotransmitter that plays a crucial role in mood regulation. Estrogen influences serotonin levels, so when estrogen drops, serotonin levels can follow, contributing to low mood.
Therefore, while other hormones play a role in overall well-being, estrogen and progesterone fluctuations are primary drivers behind hormone-related low mood.
