While melasma is a complex skin condition with multiple contributing factors, progesterone is strongly implicated as a primary hormone involved in its development.
Here's a breakdown of the hormonal influence on melasma:
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Progesterone's Role: Studies suggest that progesterone plays a significant role in the development of melasma. Postmenopausal women who receive progesterone are more likely to develop melasma than those who receive estrogen alone, highlighting progesterone's potential contribution.
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Estrogen's Influence: Although progesterone seems to be the primary driver, estrogen also plays a role. Pregnancy, hormone replacement therapy, and oral contraceptive use (which often contain both estrogen and progesterone) can trigger melasma, suggesting that estrogen can contribute, perhaps synergistically with progesterone.
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Other Contributing Factors: It is important to note that hormones are not the sole cause. Other factors that can trigger melasma include:
- Sun Exposure: Ultraviolet (UV) radiation from the sun is a major trigger for melasma.
- Genetics: A family history of melasma increases the risk.
- Certain Skin Care Products: Some products can irritate the skin and potentially contribute to melasma.
In summary, while multiple factors contribute to melasma, progesterone is a key hormone implicated in its development, often working in conjunction with other factors such as estrogen and sun exposure.
