MCH stands for Melanin-Concentrating Hormone.
Melanin-Concentrating Hormone (MCH), also sometimes referred to as pro-melanin stimulating hormone (PMCH), is a cyclic 19-amino acid orexigenic hypothalamic peptide. It was originally discovered and isolated from the pituitary gland of teleost fish. In fish, its primary function is to control skin pigmentation. However, in mammals, including humans, MCH is primarily involved in regulating feeding behavior, sleep-wake cycles, and mood.
Key Functions of MCH in Mammals:
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Appetite Regulation: MCH stimulates appetite, making it an orexigenic hormone. It plays a significant role in regulating food intake and energy balance.
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Sleep-Wake Cycles: MCH neurons are most active during sleep and play a role in promoting and maintaining sleep.
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Mood Regulation: MCH has been implicated in mood and emotional states. Research suggests that it may play a role in anxiety and depression.
Summary:
MCH stands for Melanin-Concentrating Hormone, a peptide with significant roles in regulating appetite, sleep-wake cycles, and mood in mammals.
