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What is HPV Reflex?

Published in HPV Testing 2 mins read

HPV reflex testing is a procedure performed on a Pap test sample to determine if the Human Papillomavirus (HPV) is present, especially in women with low-grade Pap test results, like ASC-US or LSIL, guiding necessary follow-up actions.

Understanding HPV Reflex Testing

When a Pap test returns an unclear or mildly abnormal result, a reflex HPV test is often conducted on the same sample to provide more information. This helps healthcare providers determine the best course of action for patient care.

The Purpose of HPV Reflex Testing

The primary goals of reflex HPV testing include:

  • Detecting HPV: Identifies the presence of the Human Papillomavirus.
  • Guiding Follow-Up: Helps decide on the appropriate next steps, such as more frequent screenings or colposcopy, based on HPV results, especially for women with ASC-US or LSIL Pap test results.

Who is Eligible?

According to the provided reference, reflex HPV testing is particularly useful for women in specific age groups with low-grade Pap test results (ASC-US or LSIL). The specific age groups may vary based on guidelines and healthcare provider recommendations.

How It Works

Here's a simplified breakdown:

Step Description
1 A Pap test is performed.
2 If the Pap test results are ASC-US or LSIL, a reflex HPV test is automatically performed on the same sample.
3 The HPV test detects the presence of high-risk HPV types.
4 The results help determine if further investigation (like a colposcopy) is needed.

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