The majority of phosphate in the body is stored in bones and teeth.
About 85% of the body's phosphorus, which is found in the form of phosphate, resides within the skeletal system. However, phosphate also exists in smaller quantities within cells and tissues throughout the body, where it plays vital roles in various biological processes.
Here's a breakdown:
- Bones and Teeth: This is the primary storage location, providing structural support and mineral density.
- Cells and Tissues: Phosphate is crucial for energy storage and transfer (as part of ATP), DNA and RNA synthesis, and cell signaling.
- Kidneys: While not a storage site, the kidneys play a critical role in regulating phosphate levels in the body by filtering waste and reabsorbing phosphate as needed.
In addition to its structural role in bones and teeth, phosphate is essential for:
- Energy Production: Phosphate is a key component of adenosine triphosphate (ATP), the body's primary energy currency.
- DNA and RNA Synthesis: The backbone of DNA and RNA molecules contains phosphate groups.
- Cell Signaling: Phosphate groups are involved in many cell signaling pathways, regulating various cellular functions.
- Kidney Function: The kidneys help maintain phosphate balance in the body.