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Can Two Sperm Fertilize One Egg?

Published in Human Reproduction 3 mins read

Yes, it's possible for two sperm to fertilize a single egg, although this is rare. This phenomenon is often associated with specific types of pregnancies and twin formations, but typically doesn't result in a viable, healthy pregnancy.

Understanding the Process

While typically one sperm fertilizes one egg, it's scientifically documented that two sperm can fertilize a single egg. This results in an embryo with three sets of chromosomes instead of the usual two (one from the mother and one from the father). This is different from the more common forms of twinning.

  • Identical twins: These develop from a single egg fertilized by a single sperm that splits after fertilization.
  • Fraternal twins: These result from two separate eggs being fertilized by two separate sperm.
  • Semi-identical twins: This extremely rare case results from one egg fertilized by two sperm. This leads to a genetically unique situation.

Outcomes of Double Fertilization

The result of two sperm fertilizing one egg is usually not viable. The extra genetic material often leads to developmental abnormalities, and the resulting pregnancy may not progress normally. In some rare instances, however, this type of fertilization has resulted in live births, though these pregnancies often present high risks.

  • Partial molar pregnancy: This occurs when an abnormal placenta forms alongside an embryo because two sperm have fertilized the egg.
  • Chimerism: In the extremely rare cases where a pregnancy resulting from double fertilization reaches term, the resulting child is a chimera, meaning their cells contain different genetic compositions (X and Y chromosomes).

Examples and Research

Several studies and news reports highlight this rare occurrence:

It is important to note that while biologically possible, this is an exceedingly uncommon event. The vast majority of conceptions involve a single sperm fertilizing a single egg.

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