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Can CBC detect IBD?

Published in IBD Diagnosis 2 mins read

A Complete Blood Count (CBC) can provide clues that may suggest Inflammatory Bowel Disease (IBD), but it cannot definitively diagnose it. A CBC is often used as part of the initial workup for IBD to look for signs of infection and anemia.

Here's a breakdown:

  • What a CBC is: A CBC is a common blood test that evaluates the different types of cells in your blood, including red blood cells, white blood cells, and platelets.

  • How it relates to IBD:

    • Anemia: IBD can cause anemia (low red blood cell count) due to chronic inflammation and blood loss in the digestive tract. A CBC can detect anemia.

    • Infection: Elevated white blood cell count (WBC) can indicate inflammation or infection, which can be present in IBD. A CBC can detect elevated WBC.

  • Why it's not a definitive test: While a CBC can show signs suggestive of IBD, these signs can also be caused by other conditions. Therefore, other tests like colonoscopy, endoscopy, stool tests, and imaging are needed for a definitive diagnosis.

IBD Blood Tests

Blood Test What it Detects Specific to IBD?
Complete Blood Count (CBC) Anemia, infection No
C-reactive protein (CRP) Inflammation No
Erythrocyte Sedimentation Rate (ESR) Inflammation No
Liver Function Tests (LFTs) Liver and bile duct problems, which are occasionally seen in some people with Crohn's disease No

As the reference states, "Routine blood tests for IBD may include: • Complete blood count (CBC) to detect infection and anemia • Inflammation markers such as C-reactive protein (CRP) and Erythrocyte Sedimentation Rate (ESR) • Liver function tests to screen for liver and bile duct problems, which are occasionally seen in some people with Crohn's ..."

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