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How does a lymphocyte work?

Published in Immune Cells Function 3 mins read

Lymphocytes are crucial white blood cells that play a central role in the body's immune system. They are primarily responsible for adaptive immunity, meaning they recognize and target specific pathogens. There are two main types of lymphocytes, each with distinct functions: B cells and T cells.

B Cells: Antibody Producers

B cells primarily function by producing antibody molecules. These antibodies are specialized proteins that bind to specific antigens, which are molecules found on the surface of invading pathogens like viruses or bacteria.

  • When a B cell encounters an antigen it recognizes, it gets activated.
  • Activated B cells multiply and differentiate into plasma cells.
  • Plasma cells are the "antibody factories" that secrete massive amounts of antibodies.
  • These antibodies circulate in the blood, latching onto pathogens and marking them for destruction by other immune cells or directly neutralizing the pathogen.

T Cells: Direct Fighters and Regulators

T cells are a diverse group that directly participate in immune responses and also regulate the immune system. They come in different subtypes, including:

  • Cytotoxic T cells (Killer T cells): These directly kill infected cells, by detecting specific antigens on the surface of infected cells.
  • Helper T cells: These don't directly kill but are crucial in activating other immune cells, including B cells and other T cells by producing cytokines.
  • Cytokines are biological substances that help activate other parts of the immune system, coordinating an immune response.

Summary Table

Lymphocyte Type Function Mechanism
B Cells Antibody production and pathogen neutralization Produce and release antibodies that bind to and neutralize specific pathogens
T Cells Direct killing of infected cells, immune regulation Kill infected cells directly. Release cytokines to activate other immune cells

How Lymphocytes Work Together

B cells and T cells work together to create a robust immune response. For example, Helper T cells can help activate B cells, stimulating them to produce more antibodies. Cytotoxic T cells work to directly kill infected cells, preventing the pathogen from replicating.

Lymphocytes are essential for adaptive immunity, providing targeted responses to specific threats. Without them, the body would be highly vulnerable to infections.

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