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How is antibody produced?

Published in Immune Response 2 mins read

Antibodies are produced by specialized immune cells called plasma cells within the human body as a key part of the adaptive immune response. This process is designed to target and neutralize invading pathogens.

Here's a breakdown of how this happens:

  • Antigen Recognition: When the body encounters a foreign substance, known as an antigen (e.g., a virus, bacteria), certain immune cells called B cells recognize this antigen.
  • B Cell Activation: Once a B cell identifies an antigen, it gets activated. This activation involves a series of complex cellular signals and interactions.
  • Differentiation into Plasma Cells: The activated B cell then differentiates into a plasma cell. Plasma cells are essentially antibody factories, dedicated to producing and releasing a large quantity of antibodies.
  • Antibody Production & Release: These plasma cells synthesize and secrete antibodies specific to the antigen that initially triggered the B cell activation. These antibodies are designed to bind specifically to that particular antigen.
  • Immune Response: The released antibodies then circulate in the bloodstream, lymph, and other body fluids. They bind to their target antigens, marking them for destruction or neutralization by other immune cells and mechanisms. This process ultimately helps to clear the infection.
Step Description
1. Antigen Recognition B cells detect foreign substances (antigens).
2. B Cell Activation B cells activate upon recognizing an antigen.
3. Plasma Cell Formation Activated B cells transform into plasma cells.
4. Antibody Production Plasma cells synthesize and release large quantities of antigen-specific antibodies.
5. Immune Action Antibodies circulate and bind to the antigens, initiating the immune response.

Essentially, the antibody production is a complex process where the immune system creates customized molecules to fight specific threats. As the reference stated, antibodies are naturally produced by plasma cells within the human body to mediate an adaptive immune response against invading pathogens.

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