Gamma disease, more precisely known as Gamma Heavy Chain Disease (γ-HCD), is a rare disorder affecting the immune system. People with this disease produce an abnormal form of the gamma heavy chain, which is a protein component normally used in the production of antibodies.
Understanding Gamma Heavy Chain Disease
Here's a more detailed breakdown:
- Abnormal Protein Production: The core issue is the overproduction of an abnormal gamma heavy chain protein.
- Impact on Immune Cells: This abnormal protein negatively affects the growth of cells in the immune system.
- Antibody Function Impairment: Because the gamma heavy chain is a crucial part of antibody structure, the abnormal version disrupts normal antibody function. This disruption can lead to various complications, including increased susceptibility to infections.
- Cellular Growth Issues: The overproduction of the faulty gamma heavy chain can trigger abnormal cell growth, contributing to the disease's pathology.
Summary
Gamma heavy chain disease involves the creation of a dysfunctional gamma heavy chain protein, disrupting the immune system and potentially leading to abnormal cell growth. This impacts the body's ability to fight off infections effectively.
