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What is IgG lambda?

Published in Immunoglobulin Subtypes 2 mins read

IgG lambda refers to a specific type of antibody and a subtype of multiple myeloma.

Understanding IgG Lambda

To understand IgG lambda, it's helpful to break down the components:

Immunoglobulin G (IgG)

  • IgG is the most common type of antibody found in the blood.
  • Antibodies are proteins produced by the immune system to help fight off harmful substances, like bacteria and viruses.
  • IgG provides long-term immunity to the body.

Lambda Light Chains

  • Antibodies are made up of heavy chains and light chains.
  • There are two types of light chains: kappa and lambda.
  • Lambda light chains combine with heavy chains to form an antibody.

IgG Lambda in Multiple Myeloma

IgG lambda multiple myeloma is a specific type of cancer where abnormal plasma cells in the bone marrow produce an excessive amount of IgG antibodies with lambda light chains. The overproduction of these abnormal proteins can cause various health problems.


Feature Description
IgG The type of antibody
Lambda Light Chain The specific type of light chain associated with the antibody
Multiple Myeloma A cancer where plasma cells produce an excessive amount of abnormal antibodies
IgG Lambda Myeloma A subtype of multiple myeloma, specifically characterized by the excessive production of IgG lambda antibodies


In summary, IgG lambda is an antibody composed of IgG heavy chains and lambda light chains. IgG lambda is also a subtype of multiple myeloma which results in abnormal plasma cells overproducing IgG antibodies with lambda light chains.

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