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How are antibodies made?

Published in Immunology Basics 2 mins read

Antibodies are produced by specialized white blood cells called B cells, in response to an antigen. Here’s a more detailed look at the process:

The Process of Antibody Production

When your body encounters an antigen (a substance that triggers an immune response), the following happens:

  • B Cell Activation: An antigen comes into contact with a B cell. This interaction activates the B cell.
  • Clonal Expansion: The activated B cell begins to divide and create many copies (clones) of itself. Each clone is specific to the particular antigen that triggered the response.
  • Differentiation into Plasma Cells: These cloned B cells differentiate into plasma cells, which are essentially antibody factories.
  • Antibody Release: The plasma cells release millions of antibodies into the bloodstream and lymph system.

Key Players in Antibody Production

Component Function
B Cells Specialized white blood cells that produce antibodies.
Antigen Any substance that triggers an immune response, leading to antibody production.
Plasma Cells Cloned B cells that are essentially antibody factories.

Why is This Important?

Antibodies are crucial to your body's defense system. They:

  • Neutralize pathogens: Antibodies can bind to pathogens, blocking their ability to infect cells.
  • Mark for destruction: Antibodies can coat pathogens, making it easier for other immune cells to recognize and destroy them.
  • Activate other immune responses: Antibodies play a role in activating other immune cells and responses, amplifying the overall immune response.

By understanding how antibodies are made, you gain insight into how your immune system protects you from disease. This process is at the heart of many medical treatments, like vaccines, which work by stimulating antibody production.

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