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What are Adaptive Defenses?

Published in Immunology 2 mins read

Adaptive defenses, also known as adaptive immunity, are a type of immunity that develops when your immune system responds to a specific foreign substance or microorganism. This response can occur after an infection or vaccination.

Here's a breakdown of adaptive immunity:

  • Specificity: Adaptive immunity is highly specific. It targets particular pathogens or foreign substances, unlike innate immunity, which provides a more general defense.

  • Memory: A key feature of adaptive immunity is its ability to "remember" previous encounters with pathogens. This immunological memory allows for a faster and more effective response upon subsequent exposure to the same pathogen. This is the basis of how vaccines work.

  • Two Main Branches: Adaptive immunity has two main branches:

    • Humoral Immunity: This branch involves B lymphocytes (B cells) and the production of antibodies. Antibodies are proteins that bind to specific antigens (foreign substances) and neutralize them or mark them for destruction by other immune cells.

    • Cell-Mediated Immunity: This branch involves T lymphocytes (T cells), which directly attack infected cells or activate other immune cells to fight infection. There are different types of T cells, including:

      • Helper T cells: Help activate B cells and cytotoxic T cells.
      • Cytotoxic T cells: Directly kill infected cells.
      • Regulatory T cells: Help suppress the immune response to prevent autoimmunity.
  • Development: Adaptive immunity is not present at birth. It develops over time as you are exposed to different pathogens or receive vaccinations.

  • Examples:

    • Developing immunity to measles after having the disease or receiving the MMR vaccine.
    • Producing antibodies against a specific strain of influenza after being infected.

In summary, adaptive defenses provide a highly specific and long-lasting form of immunity by "learning" and remembering encounters with pathogens, enabling the body to mount a faster and more effective response upon future exposure.

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