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What are CLP cells?

Published in Immunology 1 min read

CLP cells, or common lymphoid progenitor cells, are a type of immune cell that gives rise to other immune cells.

According to research, CLP cells differentiate into various immune cells, including:

  • T cells
  • B cells
  • NK cells
  • ILC3s (Innate Lymphoid Cells 3) [9–11]

During the differentiation process of CLP cells into other immune cell types, specific transcriptional regulators, such as inhibitors of DNA binding (Id) and E proteins, are expressed. This intricate regulation guides the development of diverse immune cell lineages from a common progenitor.

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