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What is the role of T cells?

Published in Immunology 2 mins read

T cells are a crucial part of the immune system, playing a vital role in protecting the body from infection and disease. They develop from stem cells in the bone marrow and are responsible for recognizing and attacking foreign invaders like bacteria, viruses, and fungi. T cells also play a role in fighting cancer.

There are two main types of T cells:

  • Cytotoxic T cells (CTLs): These cells directly kill infected cells or cancerous cells by releasing cytotoxic substances.
  • Helper T cells: These cells help activate other immune cells, such as B cells, to produce antibodies and macrophages to engulf and destroy pathogens.

T cells are essential for adaptive immunity, meaning they can recognize and remember specific pathogens, allowing for a faster and more effective response to future infections.

Examples of T cell functions:

  • Fighting viral infections: T cells recognize and kill cells infected with viruses, preventing the spread of infection.
  • Fighting bacterial infections: T cells activate macrophages to engulf and destroy bacteria.
  • Fighting cancer: T cells can recognize and destroy cancerous cells, preventing the spread of tumors.
  • Regulating immune responses: T cells help maintain immune homeostasis by controlling the activation and suppression of other immune cells.

The role of T cells in disease:

  • Autoimmune diseases: In autoimmune diseases, T cells mistakenly attack the body's own tissues, leading to inflammation and damage.
  • Allergies: T cells can contribute to allergic reactions by releasing substances that trigger inflammation.
  • Type 1 diabetes: In type 1 diabetes, T cells attack and destroy insulin-producing cells in the pancreas.

Overall, T cells are essential for a healthy immune system and play a vital role in protecting the body from a wide range of threats.

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