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What Produces Antibodies?

Published in Immunology 2 mins read

Plasma cells within the human body are responsible for producing antibodies.

The Role of Plasma Cells

  • Adaptive Immune Response: Plasma cells are specialized immune cells that are crucial for the adaptive immune response. This response is targeted and specific to invading pathogens, offering long-lasting protection.
  • Antibody Production: These cells synthesize and secrete large quantities of antibodies, also known as immunoglobulins. Antibodies are specialized proteins that recognize and neutralize foreign invaders like bacteria, viruses, and toxins.
  • Different Types of Antibodies: The human body produces five main types of antibodies, each having specific functions:
    • IgG: Most abundant antibody found in blood and tissues.
    • IgA: Present in mucous membranes and bodily secretions like tears and saliva.
    • IgM: First antibody produced during an immune response.
    • IgE: Involved in allergic reactions and fighting parasitic infections.
    • IgD: Function is less well-understood, but they are present on B cells.

Where are Plasma Cells Found?

Plasma cells are primarily found in:

  • Bone Marrow: Mature plasma cells reside in the bone marrow, where they continuously produce antibodies.
  • Lymph Nodes: During an immune response, plasma cells can also be found in the lymph nodes.
  • Spleen: The spleen is another area where antibody production can take place.
  • Infected Tissues: They can migrate to infection sites to provide focused antibody production.

Table: Antibody Production

Cell Type Function
Plasma Cells Produce and release antibodies

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