IgD's main function is to activate basophils and mast cells to produce antimicrobial factors, particularly in respiratory immune defense.
IgD's Role in Immunity
While the precise role of IgD continues to be elucidated, research indicates its importance in the following areas:
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Activation of Basophils and Mast Cells: IgD binds to basophils and mast cells, triggering them to release antimicrobial factors. This is a key component of the immune response, particularly in the respiratory system.
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Respiratory Immune Defense: The antimicrobial factors released by basophils and mast cells, when activated by IgD, are crucial for defending against respiratory infections.
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B Cell Homeostasis: IgD stimulates basophils to release factors that contribute to the maintenance and regulation of B cells (B cell homeostatic factors).
In summary, IgD plays a significant role in activating immune cells like basophils and mast cells to produce antimicrobial factors, especially in the context of respiratory defense, and is also involved in B cell homeostasis.
