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Who produces antibodies?

Published in Immunology 2 mins read

B lymphocytes, also known as B cells, are the cells that produce antibodies.

Antibodies, also called immunoglobulins, are specialized proteins that recognize and bind to specific antigens (foreign substances like bacteria, viruses, and toxins) in the body. This binding helps neutralize the antigen or marks it for destruction by other parts of the immune system.

The Role of B Lymphocytes

B lymphocytes are a type of white blood cell (lymphocyte) that plays a crucial role in the adaptive immune response. Here's a breakdown of their function:

  • Development and Maturation: B cells develop and mature in the bone marrow. During this process, they learn to recognize specific antigens.

  • Antigen Recognition: When a B cell encounters an antigen that matches its specific receptor, it becomes activated.

  • Clonal Expansion: The activated B cell undergoes clonal expansion, rapidly multiplying to create a large population of identical B cells.

  • Differentiation: Some of these B cells differentiate into plasma cells.

  • Antibody Production: Plasma cells are specialized cells whose primary function is to produce and secrete large quantities of antibodies. These antibodies are specific to the antigen that triggered the initial B cell activation.

  • Memory Cell Formation: Some activated B cells become memory B cells. These cells remain in the body for a long time and can quickly respond to a subsequent encounter with the same antigen, providing long-term immunity.

In Summary

B lymphocytes are essential for antibody production, a critical component of the body's adaptive immune response. Through their ability to recognize antigens, differentiate into plasma cells, and produce specific antibodies, B cells help protect the body from a wide range of pathogens and toxins.

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