Infants, children, and adolescents exposed to adults in high-risk categories, along with persons who inject illicit drugs or use other high-risk substances, are at the greatest risk for tuberculosis (TB).
TB risk is not evenly distributed across populations. Certain groups face significantly higher chances of contracting the disease due to various factors including exposure, compromised immune systems, and socioeconomic conditions. Understanding these risk factors is crucial for targeted prevention and treatment efforts.
Here's a breakdown of the key populations at elevated risk:
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Infants, Children, and Adolescents Exposed to High-Risk Adults: Young individuals, particularly infants, have immature immune systems, making them more susceptible to TB infection and more likely to develop severe forms of the disease, such as TB meningitis. Close contact with adults who have active TB, especially within households or close community settings, significantly increases their risk.
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Persons Who Inject Illicit Drugs: Injection drug users are at increased risk due to several factors. Shared needles and syringes can transmit TB, and substance use often leads to behaviors that increase exposure. Furthermore, drug use can compromise the immune system, making individuals more vulnerable to infection and hindering treatment adherence.
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High-Risk Substance Users: Besides those injecting drugs, individuals who use other high-risk substances may also face increased risks. This could include substances that impair immune function or lead to unstable living situations, increasing exposure to TB.
In summary, while anyone can contract TB, certain populations face a disproportionately higher risk due to factors related to exposure, immune status, and socioeconomic vulnerabilities. Targeted interventions are essential to protect these vulnerable groups.