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What antibiotic is used for GBS?

Published in Infectious Diseases 1 min read

The antibiotics most commonly used to treat Group B Streptococcus (GBS) are penicillin and ampicillin.

Here's a more detailed breakdown:

  • Penicillin: This is typically the first-line antibiotic for GBS. It's highly effective and generally well-tolerated.

  • Ampicillin: Ampicillin is another effective option, closely related to penicillin, and often used interchangeably.

  • Alternatives for Penicillin Allergy: If a patient is allergic to penicillin, alternative antibiotics are used, such as:

    • Cefazolin: A cephalosporin antibiotic, commonly used for mild penicillin allergies.
    • Clindamycin: Used if the GBS strain is susceptible.
    • Vancomycin: Used if the GBS strain is resistant to clindamycin, or if the patient has a severe penicillin allergy.

The choice of antibiotic depends on factors like the severity of the infection, allergies, and antibiotic resistance patterns in the region.

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