High bilirubin levels can be caused by several infections. While many conditions can lead to increased bilirubin, certain infections directly impact the liver or its function, resulting in bilirubin buildup.
Infections Leading to High Bilirubin
Several types of infections are associated with increased bilirubin levels:
- Bacterial Infections: Severe bacterial sepsis can cause a rise in bilirubin levels. Source: Pubmed This is due to the body's response to the infection and potential liver damage.
- Clostridial Myonecrosis: This serious infection, also known as gas gangrene, can cause high bilirubin due to its impact on the liver and overall body function. Source: Pubmed
- Relapsing Fever (Borreliosis): This bacterial infection, caused by Borrelia species, can also lead to increased bilirubin levels. Source: Pubmed
- Infectious Mononucleosis: While less common, infectious mononucleosis, caused by the Epstein-Barr virus, can sometimes cause mild liver inflammation resulting in elevated bilirubin. Source: Johns Hopkins Medicine This is usually temporary.
- Viral Hepatitis: Various forms of viral hepatitis (A, B, C, etc.) directly infect the liver and often cause significant increases in bilirubin levels, leading to jaundice. Source: VA Hepatitis
It's crucial to understand that high bilirubin isn't solely caused by infections. Other factors such as liver diseases, gallstones, and genetic conditions like Gilbert's syndrome can also contribute to elevated bilirubin. Source: Cleveland Clinic, Source: Healthline, Source: Medical News Today, Source: Mayo Clinic, Source: WebMD, Source: Verywell Health, Source: Health A doctor's diagnosis is essential to determine the underlying cause.
