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What is Core Infection?

Published in Infectious Diseases 2 mins read

Based on the provided reference, the term "core infection" is not explicitly defined. However, the reference discusses co-infection, which may be confused with "core infection." Let's clarify what co-infection is:

Co-infection refers to the simultaneous infection of a host by multiple pathogen species, or the simultaneous infection of a single cell by two or more virus particles. Therefore, understanding co-infection can provide context.

Understanding Co-infection

Co-infection involves multiple pathogens infecting the same host or cell. This can manifest in a few different ways, as described below:

  • Multi-parasite infections: A host is simultaneously infected by multiple different parasites.
  • Simultaneous viral infections: A single cell is infected by two or more virus particles at the same time. This can occur either:
    • Incrementally, where an initial infection is followed by superinfection (a second infection).
    • Simultaneously, where the cell is infected by multiple viral particles at the same time.

While "core infection" isn't a standard term, perhaps the intent was to inquire about instances where multiple infections occur, impacting the host's health and immune response.

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