Rabies, one of the oldest known diseases, has been documented as far back as 4000 years ago.
While pinpointing the exact start date of rabies is impossible due to the limitations of historical records and disease tracking, we can state that it has been recognized for millennia. The available evidence suggests its presence dates back at least 4000 years. This is evidenced by historical accounts and descriptions of rabies-like symptoms in ancient texts.
The fear associated with rabies throughout history stemmed from its almost certain fatality following infection. The ancient understanding and response to the disease reflects its devastating impact on human populations.