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Understanding CRP and Inflammation

Published in Inflammatory Markers 3 mins read

What Happens if a CRP Test is Positive?

A positive CRP test indicates the presence of inflammation somewhere in your body. This doesn't pinpoint the exact cause, but it signals that your body is actively fighting off an infection, injury, or other disease. Further testing is usually needed to determine the source of the inflammation.

C-reactive protein (CRP) is a protein produced by your liver. Its levels significantly rise in response to inflammation. Inflammation is your body's natural response to injury, infection, or disease, helping to protect and heal tissues. While acute inflammation is usually beneficial, chronic inflammation, as seen with persistently high CRP levels, can be detrimental to long-term health. Chronic inflammation is often linked to conditions like heart disease, arthritis, and autoimmune disorders.

What a Positive CRP Test Might Mean:

  • Infection: Bacterial or viral infections can trigger a high CRP level.
  • Injury: Trauma, surgery, or any tissue damage can cause inflammation and elevate CRP.
  • Autoimmune Diseases: Conditions such as rheumatoid arthritis or lupus involve chronic inflammation.
  • Inflammatory Bowel Disease (IBD): Diseases like Crohn's disease and ulcerative colitis lead to chronic gut inflammation.
  • Heart Disease: High CRP levels are associated with an increased risk of cardiovascular events.
  • Cancer: Certain cancers can cause inflammation and thus a high CRP.
  • Other Conditions: Various other conditions, such as obesity, diabetes, and metabolic syndrome, can also increase CRP levels.

Next Steps After a Positive CRP Test:

A positive CRP test alone isn't a diagnosis. Your doctor will likely order additional tests to identify the underlying cause of the inflammation. These might include:

  • Blood tests: To assess your complete blood count (CBC), organ function, and other markers of inflammation or infection.
  • Imaging tests: Such as X-rays, ultrasounds, CT scans, or MRIs, to visualize affected areas.
  • Biopsy: A tissue sample may be taken for microscopic examination in certain cases.

Reducing inflammation often requires addressing the root cause. Treatment strategies will vary depending on the underlying condition, ranging from antibiotics for infections to medication for chronic diseases or lifestyle modifications. If your CRP levels go down, it indicates your treatment is working effectively.

Important Note: The information provided here is for general knowledge and should not be considered medical advice. Always consult your healthcare provider for diagnosis and treatment. High levels of CRP may indicate a serious health condition that causes inflammation. (Source: Sept 28, 2022 reference).

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