Yes, insulin is indeed found in cerebrospinal fluid (CSF).
According to research, insulin is present in CSF at concentrations that are approximately 5–10% of those found in plasma. This suggests that insulin can cross the endothelium and mix with small amounts entering via CSF in the Virchow-Robin space. This mixture can then enter brain interstitial fluid (ISF).
| Feature | Description |
|---|---|
| Insulin in CSF | Present |
| Concentration | 5-10% of plasma levels |
| Transportation | Crosses endothelium |
| Mixing | Mixes with other inputs in Virchow-Robin space |
| Destination | Brain Interstitial Fluid (ISF) |
