Insulin is not a lipolysis. Lipolysis is the process of breaking down fats (triglycerides) into glycerol and free fatty acids. Insulin, on the other hand, inhibits lipolysis. It plays a crucial role in regulating blood sugar levels by promoting glucose uptake and storage in cells.
Insulin achieves this by:
- Inhibiting lipolysis in adipocytes (fat cells) through multiple mechanisms, such as activating phosphodiesterase 3B to reduce intracellular cAMP levels and activating the mTORC1 pathway.
- Promoting triglyceride storage by decreasing transcription of adipose triglyceride lipase.
- Increasing glucose uptake and lipogenesis in the liver and muscle tissues.
Insulin's role in inhibiting lipolysis is essential for maintaining normal fatty acid levels and preventing excessive lipid breakdown.
