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How to Mix Insulin?

Published in Insulin Mixing 3 mins read

Mixing insulin correctly is crucial for effective diabetes management. This guide explains how to safely mix different types of insulin in one syringe. Remember to always consult your doctor or diabetes educator for personalized instructions.

Preparing to Mix Insulin

Before you begin:

  • Wash your hands: Thoroughly wash and dry your hands to prevent contamination.
  • Gather supplies: You'll need your insulin vials (clear and cloudy), a syringe appropriate for the total dose, and alcohol swabs.
  • Roll cloudy insulin: Gently roll the vial of intermediate or long-acting insulin (cloudy) between your palms 10-20 times to mix it thoroughly. Do not shake.

Mixing Insulin: Clear Before Cloudy

The standard procedure is to draw up the clear, fast-acting insulin before the cloudy, slower-acting insulin. This prevents contamination of the rapid-acting insulin.

  1. Inject air: Inject air into the vial containing the slower-acting insulin (NPH or other intermediate/long-acting insulins) first. The amount of air should equal the number of units you'll be drawing.

  2. Inject air into clear insulin: Next, inject air into the vial of fast-acting insulin (regular or rapid-acting analog). Again, add an air amount equal to your required dose.

  3. Withdraw slower-acting insulin: Carefully withdraw the required amount of slower-acting insulin from its vial.

  4. Withdraw fast-acting insulin: Now withdraw the required amount of fast-acting insulin from its vial. Ensure you withdraw the correct amount, paying attention to the markings on your syringe.

Example: If you need 25 units of NPH (slower-acting) and 10 units of regular insulin (fast-acting), inject 25 units of air into the NPH vial, followed by 10 units of air into the regular insulin vial. Draw up 25 units of NPH, then draw up 10 units of regular insulin.

Important Considerations

  • Always follow your doctor's or diabetes educator's instructions as specific insulin types and dosages vary.
  • Never mix insulins unless instructed by a healthcare professional.
  • Inspect insulin vials carefully before use. Discard any that are discolored or have visible particles.
  • Learn about the types of insulin you're using to understand their action profiles and mixing requirements. Pre-mixed insulins avoid this process.
  • Using the "clear before cloudy" method ensures that the rapid-acting insulin isn't contaminated.

This process is consistent across various sources, including the provided links that emphasize the importance of proper hand hygiene, rolling cloudy insulin, injecting air before withdrawing insulin, and the "clear before cloudy" method to ensure correct mixing and prevent contamination. Remember that this information is for educational purposes only and does not substitute for advice from a healthcare professional.

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