Interleukins, which are types of cytokines involved in immune responses, are inhibited by specific biological drugs often referred to as interleukin inhibitors. These inhibitors typically work by targeting and blocking the activity of particular interleukin molecules or their receptors.
Understanding Interleukin Inhibitors
Interleukins play crucial roles in inflammation and immune regulation. In certain diseases like autoimmune disorders and inflammatory conditions, specific interleukins can be overactive, contributing to the disease process. Interleukin inhibitors are designed to neutralize the effects of these specific interleukins, helping to reduce inflammation and manage disease symptoms.
Examples of Interleukin Inhibitors
The provided reference from DrugBank lists several drugs categorized as Interleukin Inhibitors. These include drugs that directly target specific interleukins:
| Drug | Target Interleukin |
|---|---|
| Risankizumab | Interleukin-23 |
| Bimekizumab | Interleukin-17A |
| Bimekizumab | Interleukin-17F |
These drugs, such as Risankizumab and Bimekizumab, are examples of how specific interleukins like Interleukin-23, Interleukin-17A, and Interleukin-17F can be inhibited to modulate the immune system and treat associated diseases. By binding to these interleukins, the inhibitors prevent them from interacting with their receptors and triggering inflammatory responses.
