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What Diseases Cause Low Ferritin?

Published in Iron Deficiency 2 mins read

Low ferritin levels, indicating low iron stores in the body, can stem from various diseases and conditions. The most common cause is iron deficiency anemia, a condition where the blood lacks sufficient red blood cells to carry oxygen effectively. However, other health issues can also contribute to low ferritin.

Medical Conditions Associated with Low Ferritin:

  • Iron Deficiency Anemia: This is the most frequent reason for low ferritin. A lack of iron in the diet or impaired iron absorption leads to insufficient red blood cell production. [Mayo Clinic, Hematology.org]
  • Hypothyroidism: An underactive thyroid gland can interfere with iron absorption, resulting in lower ferritin levels. [Ambar Lab, SelfDecode Labs]
  • Kidney Disease: Kidney problems can compromise the production of erythropoietin, a hormone crucial for red blood cell production, indirectly impacting ferritin levels. [Ambar Lab]
  • Inflammatory Bowel Disease (IBD): Conditions like Crohn's disease and ulcerative colitis can hinder iron absorption and lead to low ferritin. [SelfDecode Labs]

Other Contributing Factors:

  • Poor Diet: An unbalanced diet lacking sufficient iron-rich foods is a major contributor to low ferritin. [Ambar Lab, SelfDecode Labs, Nature's Best]
  • Gastrointestinal Blood Loss: Conditions causing bleeding in the gastrointestinal tract, such as peptic ulcers or gastritis, can lead to iron loss and lower ferritin. [Patient.info]
  • Heavy Menstrual Bleeding: Significant blood loss during menstruation can deplete iron stores, resulting in low ferritin. [Patient.info]
  • Certain Medications: Some medications can interfere with iron absorption. [Ambar Lab]
  • Hypoferritinemia without anemia: This is a condition where ferritin is low, but the individual does not have anemia. [NCBI]

Understanding the underlying cause of low ferritin is essential for effective treatment. A healthcare professional can conduct tests and determine the appropriate course of action, which might include dietary changes, iron supplementation, or treatment for the underlying condition.

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