No, Isaac Newton was not an only child. The provided reference indicates he was the only son of his father, Isaac Newton, but it doesn't specify whether he had any sisters or half-siblings. Therefore, without additional information, we cannot definitively say he was an only child. He was the only son of his father, Isaac Newton.
The text indicates that Isaac Newton was born in the hamlet of Woolsthorpe and was the only son of a local yeoman, also named Isaac Newton, who had passed away three months prior to his birth, and of Hannah Ayscough.