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Why is Provera Used in IVF?

Published in IVF Medication 2 mins read

Provera (medroxyprogesterone acetate), a synthetic form of progesterone, is used in IVF (In Vitro Fertilization) to regulate menstrual cycles, particularly for women who ovulate irregularly or not at all.

Here's a breakdown of why Provera is beneficial in the IVF process:

  • Regulating the Menstrual Cycle: Provera helps to induce a predictable menstrual bleed. This is crucial because IVF cycles require precise timing for the administration of fertility medications. By triggering a withdrawal bleed after a course of Provera, the start of the IVF cycle can be controlled.

  • Preventing Ovarian Cysts: While not its primary purpose in IVF, Provera, similar to oral contraceptives, can help prevent the formation of ovarian cysts that might develop during the stimulation phase involving GnRH analogs.

  • For Irregular or Absent Ovulation: Provera is often prescribed for individuals who don't ovulate regularly or at all (anovulation). By inducing a period, it creates a clean slate, allowing fertility specialists to begin ovarian stimulation with other medications in a controlled manner.

In summary, Provera plays a vital role in synchronizing the menstrual cycle and preparing the body for the subsequent stages of IVF treatment, ensuring a more predictable and controlled process.

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