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How are kidneys formed?

Published in Kidney Development 1 min read

Kidneys are formed through a complex developmental process involving multiple tissue types.

The formation of the kidneys involves the following:

  • The intermediate mesoderm is responsible for forming the kidneys themselves, as well as the ureters (tubes connecting the kidneys to the bladder) and the associated blood vessels (vasculature).
  • Splanchnopleuric mesoderm contributes to the smooth muscle and connective tissue of the bladder.
  • Endoderm forms the lining of the bladder and urethra (the tube that carries urine from the bladder out of the body).
  • Neural crest cells give rise to the autonomic nervous system of the kidney, which controls functions like blood pressure regulation and fluid balance.

In summary, kidney formation is a carefully orchestrated process involving several tissue types that ultimately create a functional excretory organ.

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