There is no single "best" medicine for proteinuria, as treatment depends on the underlying cause and severity. However, certain medications are commonly used to manage proteinuria and its associated conditions.
- Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are often prescribed to reduce protein loss in the urine and control blood pressure. Common examples include captopril, enalapril, and lisinopril.
- Spironolactone is a common treatment for hyperaldosteronism, a condition that can contribute to proteinuria. It directly antagonizes aldosterone's effects in the distal nephron.
- Statins are often recommended for patients with proteinuria related to high cholesterol levels. They help lower cholesterol and may slow the progression of kidney disease.
- Finerenone (Kerendia) is a newer medication approved by the FDA for managing proteinuria in adults with chronic kidney disease (CKD) due to type 2 diabetes.
In addition to medication, lifestyle modifications such as diet changes and regular exercise can also play a significant role in managing proteinuria.
