The provided reference focuses on symptoms rather than definitively stating the biggest single indicator of kidney disease. However, based on the reference provided, a significant indicator is a change in the frequency and quantity of urine you pass, especially at night.
Here's a breakdown of related symptoms as detailed in the provided information:
- Changes in Urination: A noticeable change in how often you urinate and the amount of urine produced, particularly a more frequent need to urinate at night, can be a key sign.
- Blood in Urine: The presence of blood in your urine (haematuria) is another indicator that should be investigated.
- Changes in Urine Appearance: Alterations in the look of your urine, or persistently frothy urine, can be a sign of kidney problems.
- Swelling (Oedema): Puffiness around your legs and ankles (oedema) can indicate that your kidneys are not effectively removing fluid from your body.
While changes in urination are significant, it's important to consult a healthcare professional for diagnosis and to determine the root cause of any symptoms. Other indicators detected by medical professionals are also crucial in identifying kidney disease.