What is Normal CKD?
"Normal CKD" is a bit of a contradiction in terms, as Chronic Kidney Disease (CKD) indicates impaired kidney function. However, the term can refer to early stages of CKD where kidney function remains relatively normal, despite some damage.
The most common indicator of kidney function is the estimated glomerular filtration rate (eGFR). A healthy eGFR is generally above 90 mL/min. However, some sources suggest that an eGFR as low as 60 mL/min can be considered within the normal range if there's no other evidence of kidney disease. This highlights the complexity; a reduced eGFR alone doesn't always signify CKD.
Stages of CKD and "Normal" Function
CKD is staged based on eGFR and the presence of kidney damage. Stage 1 CKD can include a normal eGFR (90 or above) but still shows mild kidney damage. This highlights that kidney damage doesn't always directly correlate with a significant drop in eGFR.
Factors Influencing "Normal" Ranges
Age plays a significant role. Elderly individuals may have slightly lower eGFRs than younger adults without necessarily having CKD. Therefore, what constitutes a "normal" eGFR can be context-dependent.
Interpreting Test Results
A normal eGFR doesn't guarantee the absence of kidney disease. Other tests, such as urine tests and imaging scans, are crucial for a complete diagnosis.
Conclusion
The concept of "normal CKD" is misleading. Early stages of CKD might show relatively normal eGFR levels but indicate some kidney damage. A thorough evaluation beyond just eGFR is necessary to accurately diagnose and stage CKD.
