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Why Does Creatinine Increase?

Published in Kidney Health 2 mins read

Creatinine levels increase primarily due to impaired kidney function, but other factors can also contribute.

Creatinine is a waste product from muscle metabolism, normally filtered out of the blood by the kidneys and excreted in urine. Elevated creatinine levels in the blood suggest that the kidneys aren't effectively filtering this waste.

Causes of Increased Creatinine

Cause Explanation
Kidney Problems Conditions that impair kidney function, such as kidney disease, infection, or blockage, reduce the kidneys' ability to filter creatinine.
High Protein Intake Consuming large amounts of protein can lead to increased creatinine production as a byproduct of protein metabolism.
Intense Exercise Strenuous physical activity can temporarily increase creatinine levels due to muscle breakdown and increased metabolic activity.
Certain Medications/Supplements Some drugs and supplements can affect kidney function or muscle metabolism, leading to elevated creatinine.

According to MedicalNewsToday, in addition to kidney problems, a high intake of protein, intense exercise, and the use of certain medications or supplements can also result in excess creatinine.

Factors Influencing Creatinine Levels

  • Muscle Mass: Individuals with more muscle mass generally have higher creatinine levels.
  • Age: Creatinine levels can vary with age.
  • Hydration: Dehydration can lead to concentrated creatinine levels in the blood.

Therefore, while elevated creatinine often indicates kidney issues, it's crucial to consider other contributing factors for an accurate assessment.

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