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What Causes Weakness in the Legs?

Published in Leg Weakness Causes 3 mins read

Leg weakness can stem from various conditions affecting the nervous system, muscles, or circulatory system. It's crucial to consult a doctor for proper diagnosis and treatment.

Common Causes of Leg Weakness:

Here are some of the key reasons for experiencing weakness in your legs, based on the provided sources:

  • Neurological Conditions:

    • Stroke: A stroke interrupts blood flow to the brain, potentially causing muscle weakness on one side of the body, including the legs. [Source: Multiple sources including Healthline and Verywell Health]
    • Multiple Sclerosis (MS): MS is an autoimmune disease affecting the brain and spinal cord, leading to unpredictable muscle weakness and other neurological symptoms. [Source: Healthline, MedlinePlus]
    • Guillain-Barré Syndrome (GBS): This rare autoimmune disorder attacks the peripheral nervous system, causing progressive muscle weakness that can start in the legs. [Source: Healthline, MedlinePlus]
    • Amyotrophic Lateral Sclerosis (ALS): Also known as Lou Gehrig's disease, ALS is a progressive neurodegenerative disease causing muscle weakness and atrophy. [Source: eMedicineHealth]
    • Myasthenia Gravis: This autoimmune disease affects the neuromuscular junction, causing muscle weakness and fatigue. [Source: Mayo Clinic]
    • Pinched Nerve: Pressure on a nerve in the spine can radiate pain and weakness down the leg(s). [Source: Healthline]
    • Peripheral Neuropathy: Damage to the peripheral nerves, often due to diabetes or other conditions, can lead to leg weakness, numbness, and pain. [Source: Healthline, Patient.info]
  • Musculoskeletal Issues:

    • Slipped Disc: A herniated disc in the spine can compress nerves, resulting in leg weakness and pain. [Source: Healthline]
    • Sarcopenia: Age-related muscle loss and weakness. [Source: Cleveland Clinic]
  • Other Causes:

    • Peripheral Artery Disease (PAD): Narrowed arteries in the legs reduce blood flow, causing pain, cramping, and potentially weakness. [Source: American Endovascular]
    • Cancer: Some cancers can cause muscle weakness as a secondary effect. [Source: Verywell Health]
    • Diabetes: Poorly managed diabetes can damage nerves and blood vessels, resulting in leg weakness. [Source: Patient.info]
    • Nutritional Deficiencies: Deficiencies in certain vitamins (like B1, thiamine – linked to Beriberi) can contribute to muscle weakness. [Source: eMedicineHealth]

Important Note:

Leg weakness is a symptom, not a diagnosis. It's crucial to seek medical attention for proper evaluation and treatment, as the underlying cause can be serious.

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