askvity

What is the chemical name for ceramides?

Published in Lipid Chemistry 2 mins read

Ceramides are a family of lipid molecules, and their chemical names vary based on their specific structures. They are essentially composed of a sphingosine base linked to a fatty acid. The provided reference gives an example of a specific type of ceramide: N-octadecanoyl-4-hydroxysphinganine. However, this is not the general chemical name for all ceramides, rather, one specific example of a ceramide.

Ceramides in general are known as N-acylsphingosines and they are composed of:

  • A sphingosine or a similar sphingoid base.
  • An N-acyl group which is a fatty acid that is linked to the sphingoid base through an amide bond.

Let's break down the chemical name provided in the reference:

Part of the Name Explanation
N-octadecanoyl Indicates that the N-acyl group is an octadecanoyl (stearoyl) group. The prefix "octadeca" signifies 18 carbons
4-hydroxysphinganine Refers to the sphingoid base, which in this case is sphinganine (dihydrosphingosine) with a hydroxyl group at carbon 4. Phytosphingosine is used as a synonym in the reference.

The reference also specifies that N-octadecanoyl-4R-hydroxysphinganine is found in Trypanosoma brucei. This highlights that specific types of ceramides are found in different organisms.

Therefore, while "N-octadecanoyl-4-hydroxysphinganine" is a specific ceramide's chemical name, there isn't one overarching single chemical name for ceramides, as it depends on the specific fatty acid chain and sphingoid base being discussed. They are best described generally as N-acylsphingosines, with specific structures like N-octadecanoyl-4-hydroxysphinganine as one particular example.

Related Articles