An AST test, also known as the SGOT test (serum glutamic oxaloacetic transaminase test) or aspartate transaminase test, measures the amount of AST in your blood. AST is an enzyme found in your liver, heart, muscles, and other bodily tissues. A high AST level in your blood often indicates liver damage, but it can also be caused by other factors such as muscle damage. The AST test is commonly used to help diagnose liver disease or damage.
When is the AST test ordered?
- When you have symptoms of liver disease, such as fatigue, loss of appetite, yellowing of the skin or eyes (jaundice), swelling in your legs or abdomen, and dark urine.
- If you are at risk for liver disease, such as if you have a history of alcohol abuse, hepatitis, or certain medications.
- To monitor the progression of liver disease.
What do the results mean?
- Low levels of AST in the blood are usually considered normal.
- High levels of AST in the blood may be due to liver disease, heart attack, muscle injury, or other conditions.
Other Tests
An AST test is often done along with other liver function tests, such as:
- ALT (alanine transaminase): Another enzyme found in the liver.
- ALP (alkaline phosphatase): An enzyme found in the liver, bones, and intestines.
- Bilirubin: A substance produced when red blood cells are broken down.
Interpreting AST test results
It is important to note that high AST levels do not always mean you have liver disease. Other factors can cause elevated levels, so your doctor will consider your symptoms, medical history, and other test results to make a diagnosis.
