Yes, a GGT (Gamma-Glutamyl Transferase) level of 155 U/L is considered high.
GGT is an enzyme found primarily in the liver, but also in other organs like the kidneys, pancreas, and intestines. It plays a role in the metabolism of drugs and other substances. A GGT test is often used to detect liver damage or disease.
Generally, normal GGT ranges vary slightly between laboratories, but are often around:
- Men: 8-61 U/L
- Women: 5-36 U/L
A GGT of 155 U/L is significantly elevated – about 3 times higher than the upper limit of the normal range for both men and women. This level of elevation warrants further investigation by a healthcare professional to determine the underlying cause.
Potential Causes of Elevated GGT:
While a high GGT often indicates liver damage or disease, other factors can also contribute:
- Liver disease: Hepatitis (viral, alcoholic, or autoimmune), cirrhosis, non-alcoholic fatty liver disease (NAFLD), and non-alcoholic steatohepatitis (NASH).
- Alcohol abuse: Even moderate alcohol consumption can raise GGT levels.
- Bile duct obstruction: Gallstones or tumors can block the flow of bile.
- Medications: Certain medications, including some antidepressants, NSAIDs, and statins, can increase GGT levels.
- Other conditions: Congestive heart failure, diabetes, and pancreatitis can sometimes elevate GGT.
What to Do if Your GGT is High:
If your GGT level is 155 U/L (or any value outside the normal range), it's crucial to consult with your doctor. They may order further tests, such as:
- Liver function tests (LFTs): ALT (Alanine Aminotransferase), AST (Aspartate Aminotransferase), alkaline phosphatase, bilirubin, and albumin.
- Imaging studies: Ultrasound, CT scan, or MRI of the liver.
- Blood tests: To rule out specific liver diseases or other conditions.
Based on the results of these tests, your doctor can determine the cause of the elevated GGT and recommend appropriate treatment. This might include lifestyle changes (such as abstaining from alcohol or losing weight), medications, or other therapies. Given the significantly elevated level you reported, seeing a gastroenterologist or hepatobiliary specialist is a good idea to receive specialized advice and diagnostic testing.
