Yes, a bilirubin level of 40 mg/dL is significantly high. Typically, adult bilirubin levels range from 0.2 to 1.2 mg/dL. Anything above 1.2 mg/dL is considered elevated, and a level of 40 mg/dL indicates a serious condition requiring immediate medical attention.
Understanding Bilirubin Levels
Bilirubin is a yellowish substance produced when red blood cells break down. The liver processes bilirubin, and high levels usually indicate liver dysfunction or other underlying medical issues. Several references support this:
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Elevated Bilirubin and Liver Dysfunction: Studies demonstrate a clear link between high serum bilirubin levels and liver dysfunction. A high level, like 40 mg/dL, strongly suggests significant liver impairment. (Evaluating mortality and recovery of extreme hyperbilirubinemia in ...)
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Bilirubin as a Prognostic Factor: High bilirubin levels are often used as a prognostic indicator in various liver diseases, showing their importance in assessing disease severity. (Serum bilirubin: a prognostic factor in primary biliary cirrhosis) Even a pre-procedure bilirubin level can predict mortality risk. (Serum bilirubin and early mortality after transjugular intrahepatic ...)
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High Bilirubin and Mortality Risk: Research shows a strong correlation between elevated pre-treatment bilirubin levels and increased mortality risk following procedures like TIPS creation. A 40% increased risk of death is observed for each unit increase in pre-procedure bilirubin. (Serum bilirubin and early mortality after transjugular intrahepatic ...)
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Jaundice as a Symptom: High bilirubin levels cause jaundice, a yellowish discoloration of the skin and eyes. While jaundice is more common in newborns, high bilirubin in adults is a serious concern. (High Bilirubin Levels: Symptoms, Causes, Tests, and Treatments, Jaundice in Newborns - HealthyChildren.org)
Important Note: This information is for educational purposes only and does not constitute medical advice. A bilirubin level of 40 mg/dL requires immediate evaluation and treatment by a healthcare professional.
