An SGPT (Serum Glutamic Pyruvic Transaminase), also known as ALT (Alanine Aminotransferase), result of 120 IU/L indicates a moderate increase that signifies active liver inflammation or injury requiring further investigation.
Here's a more detailed explanation:
Understanding SGPT/ALT Levels
SGPT, or ALT, is an enzyme primarily found in the liver. When liver cells are damaged, they release ALT into the bloodstream, causing SGPT levels to rise. Therefore, a SGPT test is commonly used to assess liver health.
SGPT 120 IU/L: What it Suggests
According to provided reference:
- SGPT 81-120 IU/L: A moderate increase in SGPT level (specifically in the 81-120 IU/L range) signifies active liver inflammation or injury, and further workup is needed to determine the cause.
What Happens Next?
If your SGPT level is 120 IU/L, your doctor will likely order additional tests to determine the underlying cause of the liver inflammation or injury. These tests may include:
- Further blood tests: To assess other liver enzymes (like AST, alkaline phosphatase, and bilirubin) and liver function.
- Viral hepatitis testing: To check for hepatitis A, B, and C.
- Imaging studies: Such as ultrasound, CT scan, or MRI of the liver.
- Liver biopsy: In some cases, a liver biopsy may be necessary to obtain a tissue sample for examination.
Potential Causes
Elevated SGPT levels can be caused by a variety of factors, including:
- Viral hepatitis
- Alcohol abuse
- Non-alcoholic fatty liver disease (NAFLD)
- Medications
- Autoimmune hepatitis
- Genetic conditions
- Other liver diseases
