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Can a Donated Liver Grow Back?

Published in Liver Regeneration 2 mins read

Yes, a donated liver can grow back.

After a partial liver donation, the remaining portion of the donor's liver has the remarkable ability to regenerate. This is a unique characteristic of the liver that allows it to restore itself to nearly its full original size.

The Liver's Regenerative Capacity

The liver is the only visceral organ in mammals with this impressive capacity for regeneration. This means that it can regrow after a portion of it is removed. The regeneration process is not just about healing the wound; it involves the growth of new liver tissue to compensate for the lost mass.

Timeline of Liver Regeneration After Donation

Here's a general timeline of liver regeneration after donation:

  • Initial Recovery (2-4 weeks): Liver function typically returns to normal within a few weeks after the donation procedure.
  • Regrowth Phase (Up to 1 Year): The liver gradually regrows to nearly its full original volume within approximately one year.

Factors Affecting Liver Regeneration

While the liver has a robust ability to regenerate, several factors can influence the process:

  • Donor Health: The overall health of the donor plays a crucial role in how quickly and effectively the liver regenerates.
  • Surgical Technique: A skilled surgical team can minimize damage and optimize the conditions for liver regeneration.
  • Post-operative Care: Proper post-operative care, including nutrition and monitoring, is essential for successful regeneration.

Implications for Living Liver Donation

The liver's regenerative capacity makes living liver donation a viable option for individuals in need of a transplant. Because both the donor and the recipient receive a functioning liver that will eventually grow to an adequate size, this procedure can save lives.

In conclusion, while a portion of the liver is removed during donation, the remaining liver has the remarkable ability to regenerate back to nearly its original size within about a year, allowing both the donor and recipient to have a functioning liver.

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